Research group

Biomaterials

Biomaterials combine advanced material properties with biocompatibility. The research group is therefore interested in preparing smart materials that can respond to external stimuli, such as electric fields, by combining synthetic polymers, biopolymers and other materials such as metals or ceramics. The prepared materials are then tested by the lab for biocompatibility by studying the interaction with eukaryotic and prokaryotic model systems. The instrumentation allows testing of a wide range of biological properties of materials, from basic parameters such as cytotoxicity through interaction at biological interfaces to the growth of scaffolds in bioreactors. Tumour or immortalized lines or stem cells are used as model systems. In addition to biomaterials, the group also tests cosmetics, e.g. for photo-toxicity or transdermal absorption.

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.

Contacts - Research team

Implemented projects

TE02000006 - “Centre for alternative environment friendly high effective polymer antimicrobial agents for industrial applications” in consortium of Tomas Bata University and 7 companies, 2014 – 2019.

TH02020836 - “Development of novel environmentally friendly packaging with added value for food applications”, 2017-2020

GA19-16861S – „Interaction of stem cell biomaterials in simulated in vivo conditions“, 2019-2021

TH03020117 - "Conductive materials and their application for antistatic and dissipative treatment of the paper and polymeric products", 2018-2021

TG03010052 - Sub-project "Technology of recycled plastics utilization for building-decorative components", 2018-2019

TG03010052 - Sub-project "Development of biodegradable material with improved processing properties", 2018-2019

TJ01000329 - "Sensory-active polymer blends containing products of advanced extraction techniques of selected plants", 2018-2019

TJ01000330 - "Novel plastics stabilizers based on natural bioactive compounds", 2018-2019

FV10756 - “Development of polymer carriers in sub-micro and nano-forms”, 2016-2020

FV30048 - "New additives for multifunctional modification of polymeric surfaces", 2018-2021

GA17-05095S – "Biomimetic materials based on conducting polymers", 2017-2019

GA17-05318S - "Conjugated polymers based materials as luminescence chemosensors", 2017-2019

GA17-10813S - "Novel plasma polymers with tunable stability and permeability", 2017-2019

QK1910392– „Environmentally friendly soil conservation materials for the crop production intensification based on renewable resource“, 2019-2023

8X17021 - "Antibacterial polymeric nanocomposites on the base of carbon nanomaterials", 2017-2018

IGA/CPS/2018/001 – "Biological properties of polymers", 2018

IGA/CPS/2018/003 – "Functionalized polymer composites", 2018

Research outcomes

Controlling the biodegradation of polyhydroxybutyrate (PHB) and polybutylene succinate (PBS) by different types of lignin

CITATION DATA: Journal of Polymer Research, VOL: 32, ISS: 11, https://doi.org/10.1007/s10965-025-04644-1, PUBLICATION YEAR: 2025
Open in TBU repository

Unveiling the spatial architecture of biodegradable polyester plastisphere in soil and its implications for organic matter composition

CITATION DATA: Soil Biology & Biochemistry, VOL: 214, https://doi.org/10.1016/j.soilbio.2025.110050, PUBLICATION YEAR: 2026
Open in TBU repository

Optimizing electrochemical deposition for biodegradable zinc-hydroxyapatite systems in bone repair

CITATION DATA: ACS Omega, VOL: 11, ISS: 1, https://doi.org/10.1021/acsomega.5c08241, PUBLICATION YEAR: 2026
Open in TBU repository

Tuning the biodegradation rate of poly(3-hydroxybutyrate) by incorporating acidified or oxidized biochar

CITATION DATA: International Journal of Biological Macromolecules, VOL: 330, ISS: 3, https://doi.org/10.1016/j.ijbiomac.2025.148088, PUBLICATION YEAR: 2025
Open in TBU repository

Comparison of plasma polymerized thin films deposited from 2-methyl-2-oxazoline and 2-ethyl-2-oxazoline: II analysis of deposition process

CITATION DATA: International Journal of Molecular Sciences, VOL: 26, ISS: 17, https://doi.org/10.3390/ijms26178641, PUBLICATION YEAR: 2025
Open in TBU repository

Plasma mediated immobilization of metformin on polyethylene: effects on drug release, antibacterial activity, and biocompatibility

CITATION DATA: Journal of Biomaterials Science, Polymer Edition, VOL: 37, ISS: 2, https://doi.org/10.1080/09205063.2025.2524261, PUBLICATION YEAR: 2026
Open in TBU repository

Freeze-dried pickering emulsions with curcumin: The role of stabilizers and cryoprotectants

CITATION DATA: ACS Omega, VOL: 10, ISS: 26, https://doi.org/10.1021/acsomega.4c09731, PUBLICATION YEAR: 2025
Open in TBU repository

Thermoresponsive hyaluronate-based nanogels for enhanced phenanthriplatin delivery in cisplatin-resistant ovarian cancer

CITATION DATA: Biomacromolecules, VOL: 26, ISS: 8, https://doi.org/10.1021/acs.biomac.5c00692, PUBLICATION YEAR: 2025
Open in TBU repository

Dialdehyde polysaccharides as templates for green synthesis of polypyrrole-based materials without oxidative polymerization

CITATION DATA: ACS Sustainable Chemistry and Engineering, VOL: 13, ISS: 22, https://doi.org/10.1021/acssuschemeng.5c02711, PUBLICATION YEAR: 2025
Open in TBU repository

Tailoring of the physicochemical and biological properties of polypyrrole colloids with the help of stabilizers

CITATION DATA: Colloids and Surfaces A: Physicochemical and Engineering Aspects, VOL: 727, https://doi.org/10.1016/j.colsurfa.2025.138124, PUBLICATION YEAR: 2025
Open in TBU repository

Activation of NdFeB magnetic material upon exposure to oxygen plasma

CITATION DATA: Applied Surface Science, VOL: 713, https://doi.org/10.1016/j.apsusc.2025.164339, PUBLICATION YEAR: 2025
Open in TBU repository

One-step fabrication of chitosan/dialdehyde cellulose/polypyrrole composite nanofibers with antibacterial, antioxidant, and immunomodulatory effects

CITATION DATA: International Journal of Biological Macromolecules, VOL: 308, ISS: Part 1, https://doi.org/10.1016/j.ijbiomac.2025.142105, PUBLICATION YEAR: 2025
Open in TBU repository

Contacts

Head of the group: prof. Ing. Petr Humpolíček, Ph.D.

Scientific team

prof. Ing. Petr Humpolíček, Ph.D.

+420 57 603 8035 A319
+420 734 792 298
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research

Ing. Kateřina Skopalová, Ph.D.

+420 57 603 1727 A214
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doc. Zdenka Víchová, Ph.D.

+420 57 603 8047 A321
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doc. Ing. Věra Kašpárková, CSc.

+420 57 603 1232
+420 57 603 1742 A326
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doc. Ing. Marián Lehocký, Ph.D.

+420 57 603 1215 215/U1
+420 608 616 048
+420 57 603 8035 A319
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Kadir Özaltin, M.Sc., Ph.D.

+420 57 603 1741 A313/U17
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Ph.D. students

Ing. Simona Káčerová

+420 57 603 1749 A328
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Ing. Martina Martínková

+420 57 603 1749 A328
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Ing. Leona Mahelová

+420 57 603 8128 A307
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Ing. Eliška Daďová

+420 57 603 3145 A307
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Ing. Kristýna Valášková

+420 57 603 3145 A307
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Ing. Adam Srnec

+420 57 603 8128 A307
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Ing. Danila Gorgol

+420 57 603 1721 A207
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Ing. Hana Doudová

+420 57 603 1737 A228
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Ing. Michala Kurková

+420 57 603 8128 A307
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Prasad Parvathy

+420 57 603 1749 A307
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Contacts

Management


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